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  1. Opioids, such as heroin, kill more people worldwide by overdose than any other type of drug, and death rates associated with opioid poisoning in the UK are at record levels (World Drug Report 2018 [Internet]. ...

    Authors: Matthew Jones, Fiona Bell, Jonathan Benger, Sarah Black, Penny Buykx, Simon Dixon, Tim Driscoll, Bridie Evans, Adrian Edwards, Gordon Fuller, Steve Goodacre, Rebecca Hoskins, Jane Hughes, Ann John, Jenna Jones, Chris Moore…

    Citation: Pilot and Feasibility Studies 2020 6:96

    Content type: Study Protocol

    Published on:

  2. Symptoms of depression are highly prevalent and under-treated in residential aged care facilities. Behavioural activation is a simple, cost-effective psychosocial intervention that might be appropriate to help...

    Authors: Christina Bryant, Lydia Brown, Meg Polacsek, Frances Batchelor, Hannah Capon and Briony Dow

    Citation: Pilot and Feasibility Studies 2020 6:95

    Content type: Research

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  3. Patellar instability is a relatively common condition that leads to disability and restriction of activities. People with recurrent instability may be given the option of physiotherapy or surgery though this i...

    Authors: U. Rahman, E. Gemperle-Mannion, A. Qureshi, C. Edwin, T. O. Smith, H. Parsons, J. Mason, M. Underwood, J. Eldridge, P. Thompson and A. Metcalfe

    Citation: Pilot and Feasibility Studies 2020 6:94

    Content type: Research

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  5. Due to an increase in PTSD patients seeking help in the Danish mental health sector and the addition of Complex PTSD to the ICD-11, there is a need to increase efficiency of existing treatments for PTSD. mHeal...

    Authors: Frederik Bernt Scharff, Marianne Engelbrecht Lau, Lisa Helena Grønberg Riisager, Stine Bjerrum Møller, Mehrak Lykkeberg Salimi, Matthias Gondan and Sofie Folke

    Citation: Pilot and Feasibility Studies 2020 6:92

    Content type: Study Protocol

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  6. Physical activity has many physical and mental health benefits and can delay the development of disability in older age. However, uptake of this health behaviour is sub-optimal in women in their middle and old...

    Authors: Geraldine Wallbank, Catherine Sherrington, Leanne Hassett, Dominika Kwasnicka, Josephine Y. Chau, Fiona Martin, Philayrath Phongsavan, Anne Grunseit, Colleen Canning, Marian Baird, Roberta Shepherd and Anne Tiedemann

    Citation: Pilot and Feasibility Studies 2020 6:91

    Content type: Study Protocol

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  7. Huntington’s disease (HD) is an inherited neurodegenerative condition which affects movement, coordination and cognitive functioning. Psychological difficulties are commonly experienced; however, psychological...

    Authors: Fiona J. R. Eccles, David Craufurd, Alistair Smith, Rhys Davies, Kristian Glenny, Max Homberger, Siofra Peeren, Dawn Rogers, Leona Rose, Zara Skitt, Rachael Theed and Jane Simpson

    Citation: Pilot and Feasibility Studies 2020 6:90

    Content type: Research

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  8. Dry mouth is a common perioperative patient complaint. There are a number of treatments used for dry mouth in other settings which are effective. None have been tested previously in the perioperative setting. ...

    Authors: Leesa Morton, Amanda Tsan Yue Siu, Samuel Fowler, Chen Zhou, Christopher Nixon and Doug Campbell

    Citation: Pilot and Feasibility Studies 2020 6:89

    Content type: Research

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  9. Huntington’s disease (HD) is associated with a range of cognitive deficits including problems with executive function. In the absence of a disease modifying treatment, cognitive training has been proposed as a...

    Authors: Emma Yhnell, Hannah Furby, Rachel S. Lowe, Lucy C. Brookes-Howell, Cheney J. G. Drew, Rebecca Playle, Gareth Watson, Claudia Metzler-Baddeley, Anne E. Rosser and Monica E. Busse

    Citation: Pilot and Feasibility Studies 2020 6:88

    Content type: Research

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  10. Atrial fibrillation (AF) is the most common arrhythmia worldwide. Despite effective treatment, it is characterized by frequent recurrences. Optimal therapeutic management of AF requires active participation an...

    Authors: Stefan Jobst, Lynn Leppla and Stefan Köberich

    Citation: Pilot and Feasibility Studies 2020 6:87

    Content type: Research

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  11. Although older adults encompass almost half of patients with advanced chronic kidney disease, it remains unclear which long-term hemodialysis vascular access type, arteriovenous fistula or arteriovenous graft,...

    Authors: Mariana Murea, Randolph L. Geary, Denise K. Houston, Matthew S. Edwards, Todd W. Robinson, Ross P. Davis, Justin B. Hurie, Timothy K. Williams, Gabriela Velazquez-Ramirez, Benjamin Bagwell, Audrey B. Tuttle, Shahriar Moossavi, Michael V. Rocco, Barry I. Freedman, Jeff D. Williamson, Haiying Chen…

    Citation: Pilot and Feasibility Studies 2020 6:86

    Content type: Research

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  12. Charcot neuroarthropathy is a complication of peripheral neuropathy associated with diabetes which most frequently affects the lower limb. It can cause fractures and dislocations within the foot, which may pro...

    Authors: Catherine Gooday, Frances Game, Jim Woodburn, Fiona Poland, Erika Sims, Ketan Dhatariya, Lee Shepstone and Wendy Hardeman

    Citation: Pilot and Feasibility Studies 2020 6:85

    Content type: Study Protocol

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  13. Approximately, half of stroke survivors experience fatigue. Fatigue may persist for many months and interferes with participation in everyday activities and has a negative impact on social and family relations...

    Authors: David C. Gillespie, Mark Barber, Marian C. Brady, Alan Carson, Trudie Chalder, Yvonne Chun, Vera Cvoro, Martin Dennis, Maree Hackett, Euan Haig, Allan House, Steff Lewis, Richard Parker, Fiona Wee, Simiao Wu and Gillian Mead

    Citation: Pilot and Feasibility Studies 2020 6:84

    Content type: Study Protocol

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  14. Anxiety is highly prevalent in people diagnosed with bipolar disorder (BD), and can persist between acute episodes of mania and depression. Recent studies indicate that people with BD are prone to experiencing...

    Authors: Craig Steel, Kim Wright, Guy Goodwin, Judit Simon, Nicola Morant, Rod Taylor, Michael Brown, Susie Jennings, Susie Hales and Emily Holmes

    Citation: Pilot and Feasibility Studies 2020 6:83

    Content type: Study Protocol

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  15. Individuals with type 2 diabetes (T2D) who smoke are at increased risk for many types of cancers as well as an accelerated progression of microvascular and macrovascular complications. Smoking cessation is rec...

    Authors: Sydney A. Martinez, Samantha L. Quaife, Afsheen Hasan, Kathryn A. McMillan, Laura A. Beebe and Fiona Muirhead

    Citation: Pilot and Feasibility Studies 2020 6:82

    Content type: Study Protocol

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  16. It has been estimated that automated peritoneal dialysis (APD) is currently the fastest growing renal replacement therapy in the world. However, in light of the growing number of diabetic patients on peritonea...

    Authors: Karin Bergling, Javier de Arteaga, Fabián Ledesma and Carl Mikael Öberg

    Citation: Pilot and Feasibility Studies 2020 6:81

    Content type: Study Protocol

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  17. The school environment plays an essential role in promoting health education and physical activity for children and adolescence, and they are more likely to adapt it into their adulthood. School health educati...

    Authors: Aysha Almas, Romaina Iqbal, Sania Sabir, Abdul Ghani and Khawar Kazmi

    Citation: Pilot and Feasibility Studies 2020 6:80

    Content type: Study Protocol

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  18. Obesity in adolescence is predictive of obesity in adulthood and risk for chronic disease. Traditional behavioral approaches to addressing obesity in adolescence rarely yield meaningful changes in body mass in...

    Authors: Elizabeth W. Cotter, Sarah E. Hornack, Jenny P. Fotang, Elizabeth Pettit and Nazrat M. Mirza

    Citation: Pilot and Feasibility Studies 2020 6:79

    Content type: Research

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  19. Children from low-income families experience accelerated BMI gain and learning loss during summer. Healthy Summer Learners (HSL) addresses accelerated BMI gain and academic learning loss during summer by provi...

    Authors: R. Dugger, K. Brazendale, E. T. Hunt, J. B. Moore, G. Turner-McGrievy, K. Vogler, M. W. Beets, B. Armstrong and R. G. Weaver

    Citation: Pilot and Feasibility Studies 2020 6:78

    Content type: Research

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  20. In the NICU, interventions intended to enhance maternal sensitivity are indicated in order to optimize preterm infant development and long-term mother-infant attachment. A novel nursing intervention was develo...

    Authors: Andréane Lavallée, Marilyn Aita, José Côté, Linda Bell and Thuy Mai Luu

    Citation: Pilot and Feasibility Studies 2020 6:77

    Content type: Study Protocol

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  21. Complications after major surgery are a significant cause of morbidity and mortality. Neck dissection is one of the most commonly performed major operations in Head and Neck Surgical Oncology. Significant surg...

    Authors: Mandeep S. Bajwa, Stacey Carruthers, Rob Hanson, Richard Jackson, Chris Braithwaite, Mike Edwards, Seema Chauhan, Catrin Tudur Smith, Richard J. Shaw and Andrew G. Schache

    Citation: Pilot and Feasibility Studies 2020 6:76

    Content type: Study Protocol

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  22. A stroke is a sudden, life-altering event with potentially devastating consequences for survivors and their loved ones. Despite advances in endovascular and neurocritical care approaches to stroke treatment an...

    Authors: Sarah Bannon, Ethan G. Lester, Melissa V. Gates, Jessica McCurley, Ann Lin, Jonathan Rosand and Ana-Maria Vranceanu

    Citation: Pilot and Feasibility Studies 2020 6:75

    Content type: Research

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  23. The valsalva manoeuvre is an internationally recommended initial treatment for supraventricular tachycardia (SVT). The pre-hospital use of a valsalva assist device, to help deliver this manoeuvre, could improv...

    Authors: Andrew Appelboam, Jonathan Green, Paul Ewings and Sarah Black

    Citation: Pilot and Feasibility Studies 2020 6:74

    Content type: Research

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  24. Low quality social relationships in older adults are strongly associated with feelings of loneliness. Physical activity interventions could reduce loneliness and improve psychological well-being, among other h...

    Authors: Anastasia V. Shvedko, Janice L. Thompson, Carolyn A. Greig and Anna C. Whittaker

    Citation: Pilot and Feasibility Studies 2020 6:73

    Content type: Research

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  25. Very few of the publicly available apps directed towards self-management of low back pain (LBP) have been rigorously tested and their theoretical underpinnings seldom described. The selfBACK app was developed ...

    Authors: Louise Fleng Sandal, Cecilie K. Øverås, Anne Lovise Nordstoga, Karen Wood, Kerstin Bach, Jan Hartvigsen, Karen Søgaard and Paul Jarle Mork

    Citation: Pilot and Feasibility Studies 2020 6:72

    Content type: Research

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  26. Structured self-management education (SSME) for people with type 2 diabetes mellitus (T2DM) improves biomedical and psychological outcomes, whilst being cost-effective. Yet uptake in the UK remains low. An ‘Em...

    Authors: Melanie Davies, Caroline A. Kristunas, Lisa Huddlestone, Abualbishr Alshreef, Danielle Bodicoat, Simon Dixon, Helen Eborall, Agnieszka Glab, Nicky Hudson, Kamlesh Khunti, Graham Martin, Alison Northern, Mike Patterson, Rebecca Pritchard, Sally Schreder, Bernie Stribling…

    Citation: Pilot and Feasibility Studies 2020 6:71

    Content type: Research

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  27. Hip fracture is common, affecting 20% of women and 10% of men during their lifetime. The trajectory of patients’ recovery as they transition from the acute hospital setting to their usual residence is poorly u...

    Authors: Laura C. Armitage, Yuan Chi, Mauro Santos, Beth K. Lawson, Carlos Areia, Carmelo Velardo, Peter J. Watkinson, Lionel Tarassenko, Matthew L. Costa and Andrew J. Farmer

    Citation: Pilot and Feasibility Studies 2020 6:70

    Content type: Research

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  28. Mobility problems are present in 70–80% of stroke survivors and can result in impaired gait and reduced physical activity limiting independent living. Auditory rhythmic cueing (ARC) has been used to provide au...

    Authors: Patricia McCue, Silvia Del Din, Heather Hunter, Sue Lord, Christopher I. M. Price, Lisa Shaw, Helen Rodgers, Lynn Rochester and Sarah A. Moore

    Citation: Pilot and Feasibility Studies 2020 6:68

    Content type: Study Protocol

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  29. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Kimberly Legault, Mark Blostein, Marc Carrier, Susan Kahn, Sam Schulman, Sudeep Shivakumar, Cynthia Wu and Mark A. Crowther

    Citation: Pilot and Feasibility Studies 2020 6:67

    Content type: Correction

    Published on:

    The original article was published in Pilot and Feasibility Studies 2020 6:52

  30. Hypertension (HTN) affects nearly 1 billion people globally and is a major cause of morbidity and mortality. In low- and middle-income countries (LMICs), HTN represents an unmet health care gap that can be add...

    Authors: Cole Hooley, Ana A. Baumann, Vincent Mutabazi, Angela Brown, Dominic Reeds, W. Todd Cade, Lisa de las Fuentes, Enola K. Proctor, Stephen Karengera, Kenneth Schecthman, Charles Goss, Pascal Launois, Victor G. Davila-Roman and Eugene Mutimura

    Citation: Pilot and Feasibility Studies 2020 6:66

    Content type: Research

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  31. Chronic fatigue syndrome (CFS, also known as myalgic encephalomyelitis (ME)) is defined as fatigue that is disabling, is accompanied by additional symptoms and persists for ≥ 4 months. Treatment of CFS/ME aims...

    Authors: Hazel O’Dowd, Lucy Beasant, Jenny Ingram, Alan Montgomery, Will Hollingworth, Daisy Gaunt, Simon M. Collin, Sarah Horne, Beth Jones and Esther Crawley

    Citation: Pilot and Feasibility Studies 2020 6:65

    Content type: Research

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  32. Diabetic retinopathy screening (DRS) leads to the earlier detection of retinopathy and treatment that can prevent or delay the development of diabetes-related blindness. However, uptake continues to be sub-opt...

    Authors: Fiona Riordan, Emmy Racine, Susan M. Smith, Aileen Murphy, John Browne, Patricia M. Kearney, Colin Bradley, Mark James, Mark Murphy and Sheena M. McHugh

    Citation: Pilot and Feasibility Studies 2020 6:64

    Content type: Study Protocol

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  33. Globally, including in low- and middle-income [LMIC] countries, there is increased attention to and investment in interventions to prevent and respond to violence against women; however, most of these approach...

    Authors: Sarah R. Meyer, Sangeeta Rege, Prachi Avalaskar, Padma Deosthali, Claudia García-Moreno and Avni Amin

    Citation: Pilot and Feasibility Studies 2020 6:63

    Content type: Study Protocol

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  34. Strong evidence exists that substance use is a contributory risk factor for intimate partner abuse (IPA) perpetration. Men in substance use treatment are more likely to perpetrate IPA than men from the general...

    Authors: Gail Gilchrist, Sabine Landau, Polly Radcliffe, Mary McMurran, Gene Feder, Caroline Easton, Steve Parrott, Sara Kirkpatrick, Juliet Henderson, Laura Potts, Danielle Stephens-Lewis, Amy Johnson, Beverly Love, Gemma Halliwell, Sandi Dheensa, Cassandra Berbary…

    Citation: Pilot and Feasibility Studies 2020 6:62

    Content type: Study Protocol

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  35. Depression impacts the lives of millions of people worldwide. Behavioral activation (BA), derived from cognitive behavioral therapy, has the potential for improving depressive symptoms in patients with depress...

    Authors: Alessia D’Elia, Monica Bawor, Brittany B. Dennis, Meha Bhatt, Kathryn Litke, Kathleen McCabe, Jeff Whattam, Laura Garrick, Laura O’Neill, Scott Simons, Sandra Chalmers, Brenda Key, Stefanie Goyert, Phillip Laplante, Meredith Vanstone, Feng Xie…

    Citation: Pilot and Feasibility Studies 2020 6:61

    Content type: Research

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  36. Fear of cancer recurrence (FCR) is common in people affected by breast cancer. FCR is associated with increased health service and medication use, anxiety, depression and reduced quality of life. Existing inte...

    Authors: Calum T. McHale, Susanne Cruickshank, Claire Torrens, Jo Armes, Deborah Fenlon, Elspeth Banks, Tom Kelsey and Gerald M. Humphris

    Citation: Pilot and Feasibility Studies 2020 6:60

    Content type: Study Protocol

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  37. Physical inactivity and unhealthy eating are two leading behavioral risk factors contributing to preventable non-communicable diseases (NCDs). Evidence-based interventions (EBI) using community-engaged approac...

    Authors: Oluwakemi Ololade Odukoya, Steve Manortey, Michelle Takemoto, Steve Alder and Kolawole S. Okuyemi

    Citation: Pilot and Feasibility Studies 2020 6:59

    Content type: Study Protocol

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  38. Despite the benefits of physical activity for walking ability, balance, and mood, less than 30% of stroke survivors engage in recommended levels of physical activity with high levels of sedentary behaviour obs...

    Authors: Sarah A. Moore, Leah Avery, Christopher I. M. Price and Darren Flynn

    Citation: Pilot and Feasibility Studies 2020 6:58

    Content type: Study Protocol

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  39. There is a need for workplace programs promoting healthy eating and activity that reach low-wage employees and are scalable beyond the study site. Interventions designed with dissemination in mind aim to utili...

    Authors: Rachel G. Tabak, Jaime R. Strickland, Bridget Kirk, Ryan Colvin, Richard I. Stein, Hank Dart, Graham A. Colditz, Ann Marie Dale and Bradley A. Evanoff

    Citation: Pilot and Feasibility Studies 2020 6:57

    Content type: Research

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  40. Frailty is characterised by increased vulnerability to falls, disability, hospitalisation and care home admission. However, it is relatively reversible in the early stages. Older people living with frailty oft...

    Authors: Anne Heaven, Peter Bower, Bonnie Cundill, Amanda Farrin, Marilyn Foster, Robbie Foy, Suzanne Hartley, Rebecca Hawkins, Claire Hulme, Sara Humphrey, Rebecca Lawton, Catriona Parker, Neil Pendleton, Robert West, John Young and Andrew Clegg

    Citation: Pilot and Feasibility Studies 2020 6:56

    Content type: Study Protocol

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  41. Youth with autism spectrum disorder (ASD) represent a growing population with significant service needs. Prominent among these needs are high rates of co-occurring psychiatric conditions that contribute to inc...

    Authors: Kelsey S. Dickson, Gregory A. Aarons, Laura Gutermuth Anthony, Lauren Kenworthy, Brent R. Crandal, Katherine Williams and Lauren Brookman-Frazee

    Citation: Pilot and Feasibility Studies 2020 6:55

    Content type: Study Protocol

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  42. Most severe mental disorders have their onset between the age of 17 and 27, a time when many young adults begin participating in secondary or post-secondary education. The cognitive deficits typically associat...

    Authors: Lana K. M. Otto, Jacomijn Hofstra, Michelle G. Mullen, Derek Malenczak, Nynke Boonstra, Lisette van der Meer, Wim Veling, Cees Boerhout, Gerard D. van Rijsbergen, Jos de Vries, Boudien van der Pol, Gerdina H. M. Pijnenborg and Lies Korevaar

    Citation: Pilot and Feasibility Studies 2020 6:54

    Content type: Study Protocol

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  43. Polycystic ovary syndrome (PCOS) is a prevalent women’s health condition with reproductive, metabolic, and psychological manifestations. Weight loss can improve these symptoms and is a key goal; however, many ...

    Authors: Carolyn Ee, Caroline A. Smith, Michael Costello, Lisa Moran, Genevieve Z. Steiner, Nigel Stepto, Adele Cave, Atekah Albrehee and Helena Teede

    Citation: Pilot and Feasibility Studies 2020 6:53

    Content type: Study Protocol

    Published on:

  44. There is uncertainty regarding the safety and effectiveness of direct oral anticoagulant agents in patients with antiphospholipid syndrome (APS). We performed a multicenter feasibility study to examine our abi...

    Authors: Kimberly Legault, Mark Blostein, Marc Carrier, Susan Kahn, Sam Schulman, Sudeep Shivakumar, Cynthia Wu and Mark A. Crowther

    Citation: Pilot and Feasibility Studies 2020 6:52

    Content type: Research

    Published on:

    The Correction to this article has been published in Pilot and Feasibility Studies 2020 6:67

  45. Poor menstrual health and hygiene (MHH) is a globally recognised public health challenge. A pilot study of an MHH intervention was conducted in two secondary schools in Entebbe, Uganda, over 9 months. The inte...

    Authors: Ruth Nalugya, Clare Tanton, Laura Hytti, Catherine Kansiime, Kevin Nakuya, Prossy Namirembe, Shamira Nakalema, Stella Neema, Connie Alezuyo, Saidat Namuli Musoke, Belen Torondel, Suzanna C. Francis, David A. Ross, Chris Bonell, Janet Seeley and Helen A. Weiss

    Citation: Pilot and Feasibility Studies 2020 6:51

    Content type: Research

    Published on:

  46. Treatment of locally advanced oesophago-gastric adenocarcinoma usually entails neo-adjuvant chemotherapy (NAC) and surgery. Surgery is associated with high morbidity and mortality. Cardiopulmonary reserve of p...

    Authors: J. Chmelo, A. W. Phillips, A. Greystoke, S. J. Charman, L. Avery, K. Hallsworth, J. Welford and R. C. F. Sinclair

    Citation: Pilot and Feasibility Studies 2020 6:50

    Content type: Study Protocol

    Published on:

  47. Working in good jobs is associated with good health. High unemployment rates are reported in those disabled with musculoskeletal pain. Supported employment interventions work well for helping people with menta...

    Authors: Robert Froud, Mary Grant, Kim Burton, Jonathan Foss, David R. Ellard, Kate Seers, Deb Smith, Mariana Barillec, Shilpa Patel, Kirstie Haywood and Martin Underwood

    Citation: Pilot and Feasibility Studies 2020 6:49

    Content type: Research

    Published on:

  48. The guidelines for pilot and feasibility studies were published in 2016. Little is known about the guideline adherence of TCM (traditional Chinese medicine) pilot trials or whether the guidelines can significa...

    Authors: Guowei Li, Darong Wu, Xuejiao Chen, Jie Zeng, Ziyi Li and Lehana Thabane

    Citation: Pilot and Feasibility Studies 2020 6:48

    Content type: Research

    Published on:

  49. Myofascial (self-)treatments, such as foam rollers to therapeutic instruments in manual therapy, are utilized increasingly in prevention and therapy in healthy people, athletes, and patients suffering from chr...

    Authors: Patrick Weber, Christine Graf, Werner Klingler, Nadine Weber and Robert Schleip

    Citation: Pilot and Feasibility Studies 2020 6:47

    Content type: Study Protocol

    Published on:

  50. We sought to evaluate the acceptability of a psychological therapy programme (Therapy for Inter-episode Mood Variability in Bipolar Disorder (ThrIVe-B)) for individuals with ongoing bipolar mood instability an...

    Authors: Kim Wright, Gemma Palmer, Mahmood Javaid, Mohammod Mostazir and Tom Lynch

    Citation: Pilot and Feasibility Studies 2020 6:46

    Content type: Research

    Published on:

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ISSN: 2055-5784

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